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Characteristics of histopathology of choroidal neovascular membrane in age-related macular degeneration
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
- Issue:
- 2
- DOI:
- 10.3760/j.issn:1005-1015.2004.02.002
- Key Word:
- 黄斑变性/诊断;脉络膜新生血管化/诊断;吲哚花青绿/诊断应用
Abstract： 目的观察老年性黄斑变性(AMD)脉络膜新生血管(CNV) 吲哚青绿血管造影(ICGA) 表现与其组织病理学变化的关系. 方法 ICGA检查确诊的AMD患者21例21只眼,根据ICGA检查结果将CNV分成活动期、消退期、静止期,通过玻璃体切割手术取出CNV,光学显微镜、透射电子显微镜观察不同期CNV的组织病理学特征. 结果活动期CNV9只眼,组织病理学特征为大量CNV,无色素性细胞和纤维组织或有少量色素性细胞将其部分包裹;消退期CNV9只眼, 组织病理学特征为CNV较活动期减少,有较多色素性细胞、少量的纤维组织;静止期CNV3只眼,组织病理学特征为大量的纤维组织,无CNV或有极少CNV,无色素性细胞. 结论渗出型AMD患者CNV的组织病理学特征与ICGA表现具有一定的相关性.
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