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Umbilical Artery Doppler Velocimetry During Oxytocin Challenge Test and Its Clinical Significance
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PERINATAL MEDICINE
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1007-9408.2003.03.001
- Key Word:
- 催产素;脐动脉;血流速度
Abstract： 目的研究催产素激惹试验(oxytocin challenge test, OCT)在脐动脉血流异常的高危妊娠中应用价值,及OCT试验中同时行脐动脉血流检测的临床意义. 方法对170例脐动脉血管阻力增加但仍有舒张期前进血流的患者及178例脐动脉血流正常的患者行OCT试验,同时于OCT试验中子宫收缩时和收缩间歇进行脐动脉血流检测.对于OCT中子宫收缩时脐动脉血管阻力增加>0.5的阳性OCT患者于当日行剖宫产终止妊娠,余者试行阴道分娩. 结果在脐动脉血流异常组和正常组,阳性OCT发生率分别为45.3%和10.1%,差异有显著性(P<0.001), 伴子宫收缩时脐动脉血流增高>0.5的阳性OCT发生率分别为37.4%和6.7%,差异有显著性(P<0.001);对于19例OCT中没有脐动脉血流增高的阳性OCT者,15例成功阴道分娩.在阴性OCT组共有30例患者在分娩过程中因胎儿宫内窘迫进行了手术产(ODFD),其中24例患者OCT中子宫收缩时脐动脉血管阻力增加>0.5.对于不良围产期结果患者,78.6%～81.8%发生于ODFD患者. 结论 OCT结合脐动脉血流检测对弥补OCT假阳性和假阴性不足、筛选潜在宫内缺氧的脐动脉血流异常高危儿和改善围产期预后有重要临床价值.
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