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Effect of enhanced external counterpulsation on patients with coronary artery disease undergone percutaneous coronary intervention
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- Author:
- No author available
- Journal Title:
- JOURNAL OF MODERN CLINICAL MEDICAL BIOENGINEERING
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1008-634X.2006.03.003
- Key Word:
- 体外反搏;冠状动脉疾病;血管成形术,经腔,经皮冠状动脉
Abstract： 目的 探讨增强型体外反搏(enhanced external couterpulsation EECP)对冠心病经皮冠状动脉介入治疗患者的疗效.方法 经选择性冠状动脉造影确诊为冠心病且介入治疗成功的患者共469例,其中85例在药物治疗的基础上行体外反搏治疗(EECP组),另384例予单纯药物治疗(药物组).临床随访6～72个月,部分行超声心动图和冠脉造影复查,比较两组随访病例临床终点事件、左室功能和造影结果的差异.结果 (1)基线资料:对EECP组81例(95%)和药物组350例(91%)成功进行了随访,两组在临床资料、造影特征和介入治疗等方面差异均无统计学意义(P＞0.05).⑵临床终点事件:EECP组心绞痛复发率显著低于药物组(8.6%比17.4%,P＜0.05);EECP组总的临床终点事件发生率明显低于药物组(18.5%比35.4%,P＜0.01).(3)超声心动图:两组基线室壁运动指数和左室射血分数相似,但复查时EECP组明显优于药物组(P＜0.01).⑷冠状动脉造影:两组再狭窄发生率差异无统计学意义P＞0.05,但EECP组出现侧支循环患者数明显多于药物组(17.9%比5.1%,P＜0.05),复查时病变血管参考内径[(3.29±0.61)mm比(3.06±0.50)mm,P＜0.05]和支架内最小腔径[(3.02±0.59)mm比(2.67±0.62)mm,P＜0.01]均显著大于药物组.结论 对于介入治疗成功的冠心病患者,增强型体外反搏可减少心绞痛复发,改善预后和心功能,并可能有预防再狭窄的作用.
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