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脑胶质瘤动物模型的研究进展

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Author:: No author available

Journal Title:: National Medical Journal of China

Issue:: 25

DOI:: 10.3760/cma.j.issn.0376-2491.2018.25.020

Key Word:: No keyword available

Abstract：脑胶质瘤是颅内最常见的恶性肿瘤,约占颅内原发肿瘤的50 ％左右[1].大部分胶质瘤呈侵袭性生长,与周围正常脑组织界限不清,手术难以彻底切除肿瘤.尽管胶质瘤的治疗已经取得了一定的进展,由于胶质瘤的发病机制尚未完全阐述明白,胶质母细胞瘤患者的平均生存周期仅仅14.6 个月[2].因此,脑胶质瘤的研究对于提高胶质瘤的疗效和延长患者生存周期至关重要.而建立理想的动物模型是研究脑胶质瘤发病机制,以及研发新的治疗手段的关键.

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