Abstract： Objective To review the clinical aspects and pathogenesis of postpartum hemorrhage (PPH) and investigate the optimal protocols for intervention.Methods From February 2009 to December 2015,data of normal labour and casearean birth women admitted to intensive care unit (ICU) in our hospital because of hematobilia were selected.95 patients were divided into three groups (e.g ≥500-1 000 ml,≥1 000-1 500 ml,≥1 500-2 500 ml and ≥2 500 ml group) according to the bleeding volume.A retrospective analysis was performed to study the pathogenesis of PPH,organ function,surgical intervention and clinical prognosis on hemorrhage.Results The data comprised 20 504 women over the 6-year period.95 (0.463%) of which resulted in PPH and were admitted to ICU.9 of these patients with PPH unsurvived.The value of creatinine and urea nitrogen,the score of APACHE Ⅱ and the possibility of multiple organ dysfunction syndromethe (MODS) increased with the amount of bleeding (P<0.05).For patients with PPH caused by injury of birth canal and/or placenta factors,there was significant difference among three groups on amount of bleeding (P<0.05).For patients with surgical intervention such as vaginal packing,interventional treatment and exploratory laparotomy conducted in 6 hours,the volume of transfusion was(759±114) ml.The volume of transfusion was (2 000±829) ml and (4 999±1 699) ml in 6 to 12 hours intervention group and in greater than 12 hours intervention group,respectively.The volume of transfusion significant increased over intervention time.There was a statistically significant difference in all groups (P<0.05).Conclusions Classified treatment should be conducted according the classification on the amount of bleeding.Patients with severe PPH and/or tendency of organ failure should be admitted to ICU.Measures for maintenance of the function of organs are necessary,while appropriate surgical intervention is also needed based on the cooperation between ICU and obstetrical department,and the cure rate could be improved.