Abstract： Objective To investigate the long-term outcomes of off-pump coronary artery bypass grafting (OPCABG).Methods Clinical data of 1 129 consecutive patients (937 males and 192 females) with coronary artery disease receiving OPCABG at Department of Cardiovascular Surgery,Chinese PLA General Hospital between January 2000 and December 2015 was retrospectively analyzed.The age of patients ranged from 29 to 83 years,with a mean age of (62.0 ± 9.6) years.The follow-up data of the patients,including the graft patency and repeated revascularization rate,were analyzed.Results Of the 1 129 patients analyzed,1 059 cases (93.8％) were available for follow-up for 29-192 months[with a mean time of (95.6 ±34.1) months].The 5-year,10-year,15-year and 16-year graft patency rate of arterial graft was 96.1％,95.4％,93.7％ and 93.2％,respectively.The 5-year,10-year,15-year and 16-year graft patency rate of venous graft was 92.8％,81.4％,70.9％ and 68.3％,respectively.During the follow-up,69 (6.11％) patients underwent repeated revascularization procedures.Conclusion OPCABG is safe and effective with a good long-term graft patency rate.