Paper - WANFANG MED ONLINE

You Position: Home > Paper

中枢神经系统淋巴瘤:诊断的困惑,治疗的挑战

( views:398, downloads:574 )

Author:: No author available

Journal Title:: National Medical Journal of China

Issue:: 16

DOI:: 10.3760/cma.j.issn.0376-2491.2013.16.018

Key Word:: No keyword available

Abstract：中枢神经系统淋巴瘤(central nervous system lymphoma,CNSL)是一种原发或继发于中枢神经系统(CNS)的恶性肿瘤,包括脑、脊髓、脑脊膜和眼[1].它分为原发性CNSL(PCNSL)和继发性CNSL(SCNSL).PCNSL是指诊断时仅有CNS受累的淋巴瘤,而没有其他部位淋巴结或淋巴组织的侵犯.SCNSL是指继发于淋巴结或淋巴组织的淋巴瘤[1-2].CNSL的临床表现和诊断具有特殊性,疗效不佳,生存期短,受到国内外的关注[3].为此,应当积极开展临床研究来探索新的诊断及治疗方法,对于那些有高危因素的患者予以干预,延长该类患者的生命.

Reference

[1]郑文,林宁晶,谢彦,等.中枢神经系统淋巴瘤临床诊治分析[J].2011,(22).
[2]张福林,汪寅,陈宏,等.5 109例中枢神经系统肿瘤WHO新分类统计分析[J].2004,(6).
[3]Imrie,K.R.,Mahrous,M.,Berinstein,N.,etc.Impact of central nervous system (CNS) prophylaxis on the incidence and risk factors for CNS relapse in patients with diffuse large B-cell lymphoma treated in the rituximab era: A single centre experience and review of the literature[J].2012,159(1).
[4]Kirsch,M.,Al-Ali,H.K.,Niederwieser,D.,etc.Long-term follow-up of high-dose chemotherapy with autologous stem-cell transplantation and response-adapted whole-brain radiotherapy for newly diagnosed primary CNS lymphoma: Results of the multicenter ostdeutsche studiengruppe H?matologie und onkologie [J].2012,23(7).
[5]R, Lehmitz,J, Pahnke.[Involvement of CNS in leukaemia and lymphomas--CSF meningeosis and immunocytochemical phenotyping].[J].2009,77 Suppl 1.
[6]Prodduturi, Prathima.Current and Emerging Pharmacotherapies for Primary CNS Lymphoma.[J].2012,(6).
[7]Soussain,C.,Choquet,S.,Fourme,E.,etc.Intensive chemotherapy with thiotepa, busulfan and cyclophosphamide and hematopoietic stem cell rescue in relapsed or refractory primary central nervous system lymphoma and intraocular lymphoma: A retrospective study of 79 cases[J].2012,97(11).
[8]Goldschmidt,N.,Siegal,T..CNS prophylaxis in diffuse large B-cell lymphoma: If, when, how and for whom?[J].2012,26(3).
[9]Yamanaka R,Morii K,Shinbo Y,etc.Results of treatment of 112 cases of primary CNS lymphoma.[J].2008,38(5).
[10]Bourhafour, Mouna,Boutayeb, Saber,El Harroudi, Tijani,etc.Primary malignant non-Hodgkin's lymphoma of the breast: a study of seven cases and literature review.[J].2012,10.
[11]Deckert,M.,Schulte-Altedorneburg,G.,Schlegel,U.,etc.Current strategies in the diagnosis of diffuse large B-cell lymphoma of the central nervous system[J].2012,156(4).
[12]Yap,K.K.,Sutherland,T.,Liew,E.,etc.Magnetic resonance features of primary central nervous system lymphoma in the immunocompetent patient: A pictorial essay[J].2012,56(2).
[13]主编沈志祥, 朱雄增.恶性淋巴瘤[M].2011.
[14]Ferreri AJ.How I treat primary CNS lymphoma.[J].2011,118(3).
[15]Bovi J,Schultz CJ.Current management of primary central nervous system lymphoma.[J].2010,76(3).
[16]Chamberlain MC,Glantz M,Groves MD.Diagnostic tools for neoplastic meningitis: detecting disease, identifying patient risk, and determining benefit of treatment.[J].2009,36(Suppl.2).
[17]Gerstner ER,Batchelor TT.Primary central nervous system lymphoma.[J].2010,67(3).
[18]Felipe, Slaviero,Leonardo, Frighetto,Jairo, Casali Júnior,etc.Primary central nervous system lymphoma in an immunocompetent host.[J].2008,66(3A).
[19]Senzo Taguchi,Yasushi Hamamoto,Takashi Fujii,etc.Prognosis of primary central nervous system lymphoma treated with radiotherapy alone.[J].2012,30(10).
[20]M, Gelabert-González,D, Castro Bouzas,R, Serramito-García,etc.Primary central nervous system lymphoma.[J].2013,28(5).
[21]Ferreri,A.J.M.,Illerhaus,G.,Huitema,A.D.R.,etc.Rational administration schedule for high-dose methotrexate in patients with primary central nervous system lymphoma[J].2012,53(10).
[22]Glas M,Waha A,Herrlinger U,etc.Primary CNS lymphoma in the elderly: temozolomide therapy and MGMT status.[J].2010,97(3).
[23]Yuta Shibamoto,Hiroyuki Ogino,Gen Suzuki,etc.Primary central nervous system lymphoma in Japan: Changes in clinical features, treatment, and prognosis during 1985-2004[J].2008,10(4).
[24]Yamamoto W,Tomita N,Watanabe R,etc.Central nervous system involvement in diffuse large B-cell lymphoma.[J].2010,85(1).
[25]Herrlinger U,Glantz M,Schlegel U.Should intra-cerebrospinal fluid prophylaxis be part of initial therapy for patients with non-Hodgkin lymphoma: what we know, and how we can find out more.[J].2009,36(Suppl.2).
[26]Ben-Porat LS,DeAngelis LM,Panageas KS,etc.Primary central nervous system lymphoma: the role of consolidation treatment after a complete response to high-dose methotrexate-based chemotherapy.[J].2008,113(5).