Clinical characteristics and long-term prognosis of patients with ischemic and hemorrhagic stroke
- Author:
- No author available
- Journal Title:
- NATIONAL MEDICAL JOURNAL OF CHINA
- Issue:
- 13
- DOI:
- 10.3321/j.issn:0376-2491.2008.13.008
- Key Word:
- 危险因素;脑梗死;脑出血;结局;Risk factors;lschemic infarction;Intracerebral hemorrhage;Outcome
Abstract： Objective To investigate the risk factors,pathogenesis,cause of death,and outcome of different stroke subtypes.Methods The relevant data,including demographics,baseline risk factors,cause of death,and 1-year case fatality,were analyzed among 1913 consecutive hospitalized patients with ischemic and hemorrhagic stroke,599(31.3%)with intracerebral hemorrhage(ICH)and 1314 with ischemic stroke(68.7%),including 209 cases(15.9%)of total anterior circulation infarction(TACI),417 cases(31.7%)of partial anterior circulation infarction(PACI),and 186 cases(14.2%)of posterior circulation infarctions(POCI),and 502 cases(38.2%)of lacunar infarctions(LACI),1098 males and 815 females,aged 64±13(14-98).Results Multivariate analysis showed that when age and sex were adjusted,atrial fibrillation was the independent predictive factor of TACI[odds ratio(OR)=1.42,95% CI=1.25-2.31),hypertension and alcohol intake were the independent predictive factor LACI(OR=1.24,95%CI=1.02-2.18;OR=1.12,95%CI=1.03-3.04)and ICH(OR=1.84,95%CI:1.31-3.02;OR=1.04,95%CI=1.01-4.13). A negative association was observed between hypertension and TACI(OR=0.62,95%CI=0.34-0.72),atrial fibrillation and LACI(OR=0.46,95%CI=0.26-0.82),and ICH and diabetes(OR=0.56,95%CI=0.42-0.76).As compared to LACI,TACI and ICH significantly increased the risk of 1-year mortality(OR=6.21,95%CI=2.86-8.42:OR=5.86:95%CI=2.46-8.52). Conclusions Stroke subtypes have different risk factor profile, causes and outcome.1nformation on determinants of the clinical syndromes may impact on the prevention and acute phase interventions.
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