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Characteristics of recurrence of T1G3 transitional cell carcinoma of bladder
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- Author:
- No author available
- Journal Title:
- NATIONAL MEDICAL JOURNAL OF CHINA
- Issue:
- 19
- DOI:
- 10.3760/j:issn:0376-2491.2006.19.003
- Key Word:
- 膀胱肿瘤;癌;移行细胞;复发
Abstract： 目的分析T1G3膀胱移行细胞癌的复发特点.方法自北京协和医院1993至2003年的复发性膀胱移行细胞癌病例中,选择首次治疗方法相同的T1期病例72例,按病理分级分组,G3组37例,G1-2组35例.分别对首次复发时间,复发次数,复发肿瘤的数量、形态、病理分期以及复发后治疗方法等资料进行统计分析.结果T1G3组第1、2、3年及4年以上的复发率分别为29.7%、40.5%、18.9%及10.8%,T1G1-2组分别为14.3%、34.3%、31.4%及20.0%,两组比较差异有统计学意义(P=0.025).T1G3组单次复发的4例(10.8%),3次以上复发的20例(54.0%),T1G1-2组分别为17例(48.6%)和6例(17.2%),两组比较差异有统计学意义(P＜0.01).T1G3组复发后肿瘤病理分期T2期以上的32例(86.5%),T1G1-2组15例(42.8%).T1G3组最后一次复发后进行膀胱部分切除或膀胱全切治疗的35例(94.6%),T1G1-2组20例(57.1%),两组比较差异有统计学意义(P＜0.01).结论T1G3膀胱移行细胞癌治疗后近期易复发,且复发次数多,复发后多数发展为浸润癌,应当引起临床治疗上的重视,注意术后随访.
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