Abstract： Objective To investigate the effects of laser in situ keratomileusis(LASIK)for treatment of presbyopia with hypermetropi& Methods 32 presbyopia patients(64 eyes)with hypermetropia were treated by LASIK and follow-up 1 year.The preoperative sphere was+0.75 to +3.00 D and cylinder was 0.00 to +1.75 D.For distance vision correction,the target refraction was 0.00 to-0.50 D in the dominant eye.And for near vision,the target refraction was-1.50 to-2.50 D in the non-dominant eye.The measurement including refraction,uncorrected visual acuity(UCVA),near vision,Q factor of cornea and contrast sensitivity were recorded.Results At 1 year after surgery a toted of 53.1%(17/32)of all patients had binocular distance UCVA of 20/25 or better along with J3or better near,and along with J4orbetter near was 87.5%(28/32).The postoperative corneal refractive power was significant higher than preoperative[3mm:(44.12±1.38)D,5 mm:(43.42±1.53)D] and Q factor became more negative.At 1 year 87.5%(28/32)and 100.0%(32/32)of the dominant eyes treated for distance had a manifest refractive spherical equivalent within±0.50 and±1.00 D of intended correction,respectively;of the non-dominant eyes treated for near,56.2%(18/32)and 90.6%(29/32)had a manifest refractive spherical equivalent within±0.50 and±1.00 D of intended correction respectively.The difference of sensitivity was no statistically significant between preoperative and 6 months after surgery.There were 15.6% of the eyes had dry eye syndrome and 84.4% of the patients were satisfied with LASIK at 1 year after surgery.Conclusions LASIK was a effect surgery for treatment of presbyopia with hypermetropia.