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实验性近视眼巩膜金属蛋白酶活性分析
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OPHTHALMOLOGY
- Issue:
- 6
- DOI:
- 10.3760/j:issn:0412-4081.2002.06.016
- Key Word:
- No keyword available
Abstract： @@ 近视的致病原因复杂,其临床特征性改变为眼轴长度增加和眼球体积增大.近年来文献报道近视眼的组织病理改变主要与巩膜的主动生长和重新塑形有关,与结缔组织生长相同,其包括细胞外基质(extracellular matrix,ECM)不断合成和降解的过程[1].基质金属蛋白酶(matrix metallo- proteinuse,MMPs)属于锌内肽酶,在ECM的代谢调节中具有重要作用[2].我们通过对实验性近视眼巩膜中MMPs活性的测定,探讨了MMPs与近视的关系,现将结果报告如下.
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