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The present research and progress of angiopoietin in diabetic retinopathy

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Author:
No author available
Journal Title:
Chinese Journal of Ocular Fundus Diseases
Issue:
11
DOI:
10.3760/cma.j.cn511434-20210707-00364
Key Word:
血管生成素类;糖尿病视网膜病变;受体蛋白质酪氨酸激酶类;脂质代谢;综述;Angiopoietins;Diabetic retinopathy;Receptor protein-tyrosine kinases;Lipid metabolism;Review

Abstract´╝Ü Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes, and it is the main cause of vision loss in diabetic patients. Angiopoietin (Ang), a superfamily of secreted proteins, is a vascular growth factor that regulates the stability of vascular environment, participates in angiogenesis and repair, and lipid metabolism. It plays an important role in the development of DR and has become a new target for the treatment of diabetic retinopathy. With the in-depth study of Ang and the research and development of various drugs for Ang, it is expected to bring new ideas and strategies for the treatment of DR in the future.

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