You Position: Home > Paper
大鼠视神经损伤视网膜碱性成纤维细胞生长因子的表达
( views:96, downloads:16 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1671-0290.2000.02.020
- Key Word:
- 成纤维细胞生长因子,碱性;视神经/损伤;免疫组织化学
Abstract： @@ 碱性成纤维细胞生长因子(basic fibronlast growth factor,bFGF)在神经组织的发育、营养、创伤修复及再生过程中具有重要的作用[1],其在视网膜中的含量较为丰富,对视网膜的神经元起支持营养作用,在视网膜光损伤时可保护光感受器细胞的存活[2],而在视神经损伤中视网膜bFGF的作用不明确,现将本研究报道如下.
- [1]E G, Faktorovich,R H, Steinberg,D, Yasumura,etc.Basic fibroblast growth factor and local injury protect photoreceptors from light damage in the rat.[J].1992,12.
- [2]S E, Connolly,L M, Hjelmeland,M M, LaVail.Immunohistochemical localization of basic fibroblast growth factor in mature and developing retinas of normal and RCS rats.[J].1992,11.
- [3]Linxi Li,Ronald W. Openheim,Ming Lei,etc.Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse[J].1994,25(7).
- [4]Song Y,Yasumura D,Cheng T,etc.Injury-induced upregulation of bFGF and CNTF mRNAS in the rat retina.[J].1995,15(11).
- [5]MARY E. CARWILE,RICHARD B. CULBERT,RACHEL L. STURDIVANT,etc.Rod Outer Segment Maintenance Is Enhanced in the Presence of bFGF, CNTF and GDNF[J].1998,66(6).
- [6]Faktorovich, E.G.,Steinberg, R.H..Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor.[J].1990,347(6288).
- [7]周延冲.多肽生长因子--基础与临床[M].1992.