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Preventing Rh alloimmunization during pregnancy: interpretation of clinical guidelines
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Perinatal Medicine
- Issue:
- 5
- DOI:
- 10.3760/cma.j.cn113903-20211113-00948
- Key Word:
- Rh同种免疫;Rho（D）免疫球蛋白;临床方案;诊疗准则（主题）;Rh isoimmunization;Rho(D) immune globulin;Clinical protocols;Practice guidelines as topic
Abstract： Rh alloimmunization can lead to serious fetal complications, such as hemolysis, anemia, edema, and even intrauterine death. However, there is no domestic clinical guideline for prophylaxis and management of Rh alloimmunization. This review aims to interpret the key points from international clinical guidelines, consisting of the timing of routine antibody screening and anti-Rh(D) immunoglobulin prophylaxis strategies for Rh-negative pregnant women, possible sensitization events and anti-D prophylaxis of Rh alloimmunization, and postpartum prophylaxis for unsensitized Rh-negative pregnant women.
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