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Application of immune checkpoint inhibitors in liver transplantation recipients for hepatocellular carcinoma

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Author:
No author available
Journal Title:
Chinese Journal of Organ Transplantation
Issue:
5
DOI:
10.3760/cma.j.cn421203-20211113-00279
Key Word:
肝移植;肝癌;排斥反应;免疫检查点抑制剂

Abstract: 以免疫检查点抑制剂为代表的免疫治疗在肝癌综合治疗中的地位日益提高。肝癌肝移植受者特殊的免疫抑制状态和潜在的排斥反应风险导致这部分群体的免疫治疗仍处于早期探索阶段。通过预测排斥反应发生风险、优化免疫抑制方案、有效预防急性排斥反应和探寻最佳免疫检查点抑制剂,肝癌肝移植受者将有望从免疫治疗中获益。

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