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异基因造血干细胞移植后血栓性微血管病的诊治进展

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Author:: No author available

Journal Title:: Chinese Journal of Organ Transplantation

Issue:: 8

DOI:: 10.3760/cma.j.cn421203-20200929-00346

Key Word:: 造血干细胞移植;血栓性微血管病;贫血

Abstract：本文旨在对异基因造血干细胞移植(HSCT)后移植相关血栓性微血管病(TA-TMA)的诊治最新进展做一综述。临床常常由于早期诊断比较困难而延误治疗，死亡率较高，是HSCT后最难以识别和处理的并发症之一。最近研究表明，补体激活在TA-TMA的发生过程发挥了重要作用。随着对TA-TMA病理生理机制的认识不断完善，加快了研发新的治疗药物的步伐，可为临床提供参考。

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