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The impact of vasoactive drugs on liver transplant recipients and allografts in donors after cardiac death

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Author:
No author available
Journal Title:
Chinese Journal of Organ Transplantation
Issue:
7
DOI:
10.3760/cma.j.issn.0254-1785.2013.07.008
Key Word:
肝移植;心脏死亡器官捐献;血管活性药物;Liver transplantation;Donation after cardiac death;Vasoactive agonists

Abstract: Objective To define the impact of vosoactive drugs on liver transplant recipients and allografts in donors after cardiac death (DCD).Method From July 2011 through July 2012,19 liver transplantations were performed from DCD.Donor and recipient characteristics,posttransplant complications,and patient and allograft survival time in both groups with or without use of vasoactive drugs were compared.Results No differences in liver functions (ALT,AST,GGT,TB,INR),primary graft disfunction,hepatic artery thrombosis,portal vein stenosis,or biliary complications were noted between two groups.The survival time in vasoactive drugs group was 4.2 ± 4.2 months and that in non-vasoactive drugs group was 6.2 ± 4.2 months,respectively (P > 0.05).Conclusion The application of vasoactive drugs has no influence on liver function,primary graft disfunction,hepatic artery thrombosis,portal vein stenosis,biliary complications and survival time in DCD in comparison with DCD not given vasoactive drugs.

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