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肝移植急性排斥反应的细胞及分子免疫学研究进展
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF ORGAN TRANSPLANTATION
- Issue:
- 6
- DOI:
- 10.3760/cma.j.issn.0254-1785.2007.06.022
- Key Word:
- No keyword available
Abstract： @@ 目前,肝移植已经成为治疗各种终末期肝病的有效措施,而急性排斥反应(AR)则是肝移植术后最常见的并发症之一,其组织病理学表现主要是:汇管区混合炎症细胞浸润、胆管炎和血管内皮炎.肝移植后AR是一种以细胞免疫为主、体液免疫为辅的特异性免疫反应,但肝脏由于其自身解剖和生理学因素以及一些非实质细胞的影响,使其在发生AR时具有与其他移植器官不同的特点.在肝移植AR过程中,众多的肝非实质细胞通过各种分子机制发挥着各自不同的功能,现分述如下:
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