Abstract: Colorectal cancer is a common malignant tumor of digestive system.Liver metastasis is a serious clinical problem;effective treatments and interventions can greatly prolong the survival time and improve the prognosis of patients.Comprehensive treatments based on appropriate surgical excision methods and timing and reliable adjuvant measures are the main treatment strategies for colorectal cancer liver metastasis.Multidisciplinary team diagnosis and treatment model is recommended in clinical practice for the full assessment and individualized treatment.