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内镜下套扎术与凝血酶夹心联合法治疗食管静脉曲张急性出血的研究
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- Author:
- No author available
- Journal Title:
- CHINA MEDICINE
- Issue:
- 6
- DOI:
- 10.3760/cma.j.issn.1673-4777.2007.06.014
- Key Word:
- 食管静脉曲张;急性出血;内镜治疗
Abstract： 目的 观察内镜下食管静脉曲张套扎术(EVL)与凝血酶夹心联合法治疗食管静脉曲张活动性出血的临床疗效,并与内镜下硬化治疗术(EIS)进行比较.方法 65例食管静脉曲张活动性出血的肝硬化患者被随机分为EVL与凝血酶夹心联合法组(治疗组)34例,EIS组(对照组)31例.治疗组先用套扎法每条曲张静脉结扎两点,再于两结扎点曲张静脉内注射凝血酶250 U(加生理盐水5ml),对照组用硬化剂注射法进行治疗,直到出血停止为止.结果 治疗组控制活动性出血的止血率为97%,而对照组为80%(P＜0.01);输血量治疗组(3.4±1.2)U明显低于对照组(4.6±1.8)U(P＜0.01);1个月再出血率治疗组为18%,对照组为35%(P＞0.05).结论 EVL与凝血酶夹心联合法控制食管静脉曲张活动性出血在有效性、合并症方面优于对照组.我们认为在控制食管静脉曲张活动性出血时,EVL与凝血酶夹心联合法作为推荐选择方法.
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