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适应性免疫应答在牙周炎发生中的作用

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Author:: No author available

Journal Title:: Chinese Journal of Stomatology

Issue:: 2

DOI:: 10.3760/cma.j.issn.1002-0098.2013.02.013

Key Word:: No keyword available

Abstract：牙周炎是牙周菌斑微生物引发的炎症性破坏性疾病.牙周炎的病因复杂,除与个体遗传因素有关外,已经证明宿主对抗牙周菌斑微生物的免疫应答在牙周炎的发生过程中发挥重要作用[1-2].免疫应答包括固有免疫应答和适应性免疫应答.固有免疫应答是体内固有免疫细胞(单核吞噬细胞、树突细胞等)和固有免疫分子(急性期蛋白、细胞因子等)非特异性地识别、结合病原体及其产物或其他抗原性异物后被迅速活化,并产生相应的生物学效应,从而将病原体等抗原性物质杀伤、清除的过程.

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