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Effect of hypoxia-inducible factor-1α in coupling function with angiogenesis-osteogenesis

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Author:: No author available

Journal Title:: CHINESE JOURNAL OF STOMATOLOGY

Issue:: 11

DOI:: 10.3760/cma.j.issn.1002-0098.2010.11.017

Key Word:: No keyword available

Abstract：骨缺损区的骨膜与血管受损后组织和细胞处于低氧状态,低氧导致一系列转录诱导因子的表达,它们参与了血管生成、铁、糖代谢及细胞的生长和增殖,其中缺氧诱导因子(hypoxia-inducibIe factor,HIF)1α对血管的发生及细胞的增殖起决定性作用[1].

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