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Associations between periodontal status and delivery outcomes in pregnant women with a diagnosis of threatened premature labor
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF STOMATOLOGY
- Issue:
- 10
- DOI:
- 10.3760/j.issn:1002-0098.2006.10.009
- Key Word:
- 牙周炎;妊娠结局;先兆早产
Abstract： 目的 通过比较先兆早产(TPL)孕妇与健康孕妇的牙周状况,对牙周病变程度、血清肿瘤坏死因子α(TNF-α)水平与早产间的关系作初步探讨.方法 收集TPL孕妇40例(TPL组),同期做定期产前检查无产兆的健康孕妇40名(对照组).TPL组中26例足月产(TPL-TB),14例早产(TPL-PB);对照组均足月产.检查记录菌斑指数(PLI)、探诊深度(PD)、临床附着丧失(CAL)和出血指数(BI),并计算牙周炎位点(PD＞3 mm,CAL≥2 mm)率.ELISA法检测血清TNF-α水平.结果 TPL组的PLI(0.94±0.05)、牙周炎位点率(2.93%)和血清TNF-α水平[14.81 ng/L(13.40～15.64ng/L)]均明显高于对照组的0.59±0.03、1.32%和11.47 ng/L(10.82～12.86 ng/L),P＜0.001.TPL-PB组的PLI(0.96±0.06)、BI(2.99±0.14)、牙周炎位点率(3.61%)和TNF-α水平[18.35ng/L(15.47～31.94 ng/L)]显著高于TPL-TB组的0.66±0.04、2.76±0.12、2.25%和13.70 ng/L(12.64～14.80ng/L).分娩孕周和牙周炎位点率、TNF-α水平呈显著负相关(P＜0.05),TNF-α水平与牙周炎位点率呈显著正相关(P＜0.05).结论 牙周感染可能是早产的原因之一.
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