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Prevalence of putative periodontal microorganisms in Chinese patients with aggressive periodontitis
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF STOMATOLOGY
- Issue:
- 6
- DOI:
- 10.3760/j.issn:1002-0098.2006.06.009
- Key Word:
- 牙周炎;牙菌斑;聚合酶链反应;龈下微生物
Abstract： 目的检测侵袭性牙周炎(AgP)患者和牙周健康者龈下菌斑中的7种病原微生物,旨在寻找AgP的主要致病微生物.方法应用以16S rRNA为基础的聚合酶链反应(PCR)技术,检测55例AgP患者和17名健康对照者龈下菌斑中的7种牙周病原微生物:伴放线放线杆菌(Aa),牙龈卟啉单胞菌(Pg),福赛坦氏菌(Tf),牙密螺旋体(Td),直肠弯曲杆菌(Cr),中间普氏菌(Pi),变黑普氏菌(Pn).结果55例AgP患者中仅有1例检测出Aa,而在健康对照者中未检出该菌.Pg、Tf、Td和Cr在AgP组的检出率分别为81.8%、83.6%、80.0%和81.8%,显著高于健康对照者(17.6%、11.8%、5.9%、29.4%),差异有统计学意义(P＜0.01).结论Pd、Tf、Td和Cr 4种微生物在AgP患者中有较高的检出率,提示它们的共同定植可能在AgP中起重要作用.
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