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Serum level of prostate specific antigen and its relationship with prostatic biopsy in health check-up populations

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Journal Title:
Chinese Journal of Health Management
Key Word:
体格检查;抗原;前列腺;Physical examination;Antigens;Prostate

Abstract´╝Ü Objective To study serum level of prostate specific antigen (PSA) by age and its relationship with positive prostatic biopsy.Methods A total of 8818 adults who underwent PSA scanning at Health Chek-up Center of Beijing Hospital during July 2009 and July 2010 were retrospectively studied,40 of whom performed prostatic biopsy.Linear regression was used to assess the relation of PSA with age,while Chi-square test was used to compare positive prostatic biopsy in different PSA groups.Results Serum PSA of more than 4 μg/L was more commonly seen in the elderly group (40 ~ year-old group 1.4%,50 ~ yearold group 1.9%,60 ~ year-old group 9.2%,70 ~ year-old group 15.5%,80 year-old group 17% ; P <0.001 ; RR =0.196).In those whose PSA was > 20 μg/L,6 (83.3 %) were found to have positive prostatic biopsy; and the figure was 10 (50.0%) or 24 (24.0%) when PSA was <4 μg/L or 4-10 μg/L group (P =0.048).Conclusions Age was positively correlated with PSA,although no linear correlation was confirmed.Higher serum PSA level (> 4 μg/L) may be more common in elderly people and those with a positive prostatic biopsy.

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