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Researches in serum biomarkers in diagnosis of acute exacerbation of chronic obstructive pulmonary disease

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Author:: No author available

Journal Title:: International Journal of Respiration

Issue:: 19

DOI:: 10.3760/cma.j.cn131368-20200716-00616

Key Word:: 肺疾病，慢性阻塞性;诊断;血清生物标志物;Pulmonary disease, chronic obstructive;Diagnosis;Serum biomarker

Abstract： Chronic obstructive pulmonary disease (COPD) can be divided into stable stage and acute exacerbation stage characterized by chronic airway inflammation, emphysema and incompletely reversible airflow limitation.Acute exacerbation of COPD (AECOPD) is not only complicated in etiology and poor in prognosis, but also prones to recurrent attacks.Early diagnosis and reasonable treatment are very important.As objective indexes in evaluating the disease status, serum biomarkers provide objective judgements of health status in AECOPD.This article reviewed the research progress of serum biomarkers related to AECOPD diagnosis in recent years, so as to provide references in the early warning and treatment of AECOPD.

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