Paper - WANFANG MED ONLINE

You Position: Home > Paper

Research progress of miR-142-3p in inflammation reaction and immune system

( views:166, downloads:111 )

Author:: No author available

Journal Title:: International Journal of Respiration

Issue:: 10

DOI:: 10.3760/cma.j.cn131368-20190816-01162

Key Word:: 炎症;免疫;外泌体;miR-142-3p;Inflammation;Immune system;Exosome;miR-142-3p

Abstract： miR-142-3p, a kind of 19 to 24 nucleotide-long, single-stranded RNAs, is widely related with the initiation and development of numerous diseases and negatively regulates gene expression by binding to the 3′-UTR of target messenger RNAs.miR-142-3p regulates the inflammatory response and the function of immune cells, as well as playing an important role in inflammation diseases such as osteoarthritis and sepsis, and immune related diseases including multiple sclerosisand systemic lupus erythematosus.As it could be delivered to target tissue by exosomes, miR-142-3p is expected to be a new target for the treatment of inflammation and immune related diseases.

Reference

[1]郭蕾.ARDS 患者中血清 microRNAs 生物标志物的筛选[J].2016,(18).
[2]蔡妩扬,蒋骏航,钱峰.HMGB1研究进展[J].2019,(3).
[3]F, Guo,S C, Lin,M S, Zhao,etc.microRNA-142-3p inhibits apoptosis and inflammation induced by bleomycin through down-regulation of Cox-2 in MLE-12 cells.[J].2017,50(7).
[4]Odum,N.,Hagedorn,P.H.,Bangsgaard,N.,etc.Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice[J].2012,67(5).
[5]Liu, Yin,Song, Xiaoqi,Meng, Shu,etc.Downregulated expression of miR-142-3p in macrophages contributes to increased IL-6 levels in aged mice[J].2016,80.
[6]Talebi Farideh,Ghorbani Samira,Chan Wing Fuk,etc.MicroRNA-142 regulates inflammation and T cell differentiation in an animal model of multiple sclerosis[J].2017,14(1).
[7]Peralta E,Kang X,Jain R,etc.MicroRNA-143 regulates adipocyte differentiation.[J].2004,279(50).
[8].The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14[J].1993,75(5).
[9]Martin,R.Z.,Droin,N.,Bastie,J.-N.,etc.A role for miR-142-3p in colony-stimulating factor 1-induced monocyte differentiation into macrophages[J].2013,1833(8).
[10]Ebert MS,Sharp PA.MicroRNA sponges: progress and possibilities.[J].2010,16(11).
[11]WANG HAICHAO,YANG HUAN,CZURA CHRISTOPHER J.,etc.HMGB1 as a Late Mediator of Lethal Systemic Inflammation[J].2001.
[12]Zhou,Q.,Haupt,S.,Prots,I.,etc.miR-142-3p is involved in CD25+ CD4 T cell proliferation by targeting the expression of glycoprotein A repetitions predominant[J].2013,190(12).
[13]Yin,H.,Zhao,M.,Wang,Y.,etc.Decreased microRNA-142-3p/5p expression causes CD4+ T cell activation and B cell hyperstimulation in systemic lupus erythematosus[J].2012,64(9).
[14]Gloria, Bertoli,Claudia, Cava,Isabella, Castiglioni.MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer.[J].2015,5.
[15]Jian, Zhang,Wei-feng, Shan,Te-te, Jin,etc.Propofol exerts anti-hepatocellular carcinoma by microvesicle-mediated transfer of miR-142-3p from macrophage to cancer cells.[J].2014,12.
[16]Wang, Yi,Ouyang, Min,Wang, Qiong,etc.MicroRNA-142-3p inhibits hypoxia/reoxygenation-induced apoptosis and fibrosis of cardiomyocytes by targeting high mobility group box 1[J].2016,38(5).
[17]Zahra,Naseri,Reza Kazemi,Oskuee,Mahmoud Reza,Jaafari,etc.Exosome-mediated delivery of functionally active miRNA-142-3p inhibitor reduces tumorigenicity of breast cancer in vitro and in vivo.[J].2018,13.
[18]Li, Hongdan,Li, Feng.Exosomes from BM-MSCs increase the population of CSCs via transfer of miR-142-3p[J].2018,119(6).
[19]Wang, Han,Yu, Tingting,Liu, Xiaoxiao,etc.miR-1271 inhibits migration, invasion and epithelial-mesenchymal transition by targeting ZEB1 and TWIST1 in pancreatic cancer cells[J].2016,472(2).
[20]Sun Y,Varambally S,Maher CA,etc.Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality.[J].2011,117(23).
[21]Luisa Pascucci,Valentina Coccè,Arianna Bonomi,etc.Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery[J].2014,192.
[22]Yoshida,T.,Miyazawa,T.,Kurata-Miura,K.,etc.MiR-142-3p enhances FcεRI-mediated degranulation in mast cells[J].2014,443(3).
[23]Boomer JS,To K,Chang KC,etc.Immunosuppression in patients who die of sepsis and multiple organ failure.[J].2011,306(23).
[24]Camussi G,Deregibus MC,Bruno S,etc.Exosomes/microvesicles as a mechanism of cell-to-cell communication.[J].2010,78(9).
[25]Landthaler M.,Dorsett Y.,Tuschl T.,etc.Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing[J].2004,10(3).
[26]Shu Fang Liu,Malik, Asrar B..NF-κB activation as a pathological mechanism of septic shock and inflammation.[J].2006,34(4).
[27]Yu, Hong,Wang, Chunyan,Guo, Yanqing,etc.MicroRNA-142-3p Inhibits Chondrocyte Apoptosis and Inflammation in Osteoarthritis by Targeting HMGB1[J].2016,39(5).
[28]David P. Bartel.MicroRNAs: Target Recognition and Regulatory Functions[J].2009,136(2).
[29]Paulo,Bettencourt.Actin-binding protein regulation by microRNAs as a novel microbial strategy to modulate phagocytosis by host cells: the case of N-Wasp and miR-142-3p.[J].2013,3.
[30]Rana TM.Illuminating the silence: understanding the structure and function of small RNAs[J].2007,8(1).
[31]Su Qiang,Lv Xiangwei,Ye Ziliang,etc.The mechanism of miR-142-3p in coronary microembolization-induced myocardiac injury via regulating target gene IRAK-1[J].2019,10(2).
[32]Yilun, Wang,Jun, Liang,Haihong, Qin,etc.Elevated expression of miR-142-3p is related to the pro-inflammatory function of monocyte-derived dendritic cells in SLE.[J].2016,(1).
[33]Zhen, Jie,Chen, Wei.MiR-142 inhibits cecal ligation and puncture (CLP)-induced inflammation via inhibiting PD-L1 expression in macrophages and improves survival in septic mice[J].2018,97.
[34]Rivkin, Natalia,Chapnik, Elik,Mildner, Alexander,etc.Erythrocyte survival is controlled by microRNA-142[J].2017,102(4).
[35]Bao, Han,Chen, Yuan-Xiu,Huang, Kai,etc.Platelet-derived microparticles promote endothelial cell proliferation in hypertension via miR-142-3p[J].2018,32(7).
[36]Zeng Y.Principles of micro-RNA production and maturation.[J].2006,25(46).
[37]Orom UA,Kauppinen S,Lund AH.LNA-modified oligonucleotides mediate specific inhibition of microRNA function.[J].2006,372.
[38]江伟伟,李文放.miRNA-142-3p对肺泡巨噬细胞炎症过程的负向调控及其机制[J].2017,(3).