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Inhibition of growth and metastasis of tumor by angiogenesis inhibitor endostatin
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- Author:
- No author available
- Journal Title:
- INTERNATIONAL JOURNAL OF RESPIRATION
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1673-436X.2009.02.009
- Key Word:
- 内皮抑素;血管生成;肿瘤生长和转移;Endostatin;Angiogenesis;Tumor growth and metastasize
Abstract： The growth and metastasis of malignant tumors depend on angiogenesis. Antiangiogenesis of tumor is a new therapy in recent years, and is extensively and deeply researched. Endostatin, the C-term inalproteolytic fragment of collagen Ⅹ Ⅷ ,is a potent endogenous angiogenesis inhibitor, has significant effect on antiangiogenesis of tumor, and provides a new way for the treatment of malignant tumor. The article summarizes the research advancement of inhibiting tumor growth and metastasis regarding endostatin.
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