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Prograss in DNA vaccines for prophylaxis and treatment of allergic respiratory disease
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- Author:
- No author available
- Journal Title:
- INTERNATIONAL JOURNAL OF RESPIRATION
- Issue:
- 10
- DOI:
- 10.3760/cma.j.issn.1673-436X.2006.10.014
- Key Word:
- DNA疫苗;过敏性疾病;呼吸道疾病
Abstract： 呼吸道过敏性疾病发病率一直居高不下,目前临床上治疗该病的方法效果均不够理想,DNA疫苗的Th1型免疫应答诱导能力和它在多种水平调节免疫反应的能力使它成为一种很有前途的过敏性疾病预防和治疗措施.本文综述了目前DNA疫苗预防和治疗呼吸道过敏性疾病的进展、DNA疫苗的优缺点以及相应的改进措施.
- [1]Wolfgang W, Leitner,Josef, Thalhamer.DNA vaccines for non-infectious diseases: new treatments for tumour and allergy.[J].2003,3(4).
- [2]William W, Storms.Unmet needs in the treatment of allergic asthma: potential role of novel biologic therapies.[J].1900,9(6).
- [3](美) H. C. J. 埃特尔主编 李琦涵, 刘龙丁, 车艳春主译.DNA疫苗[M].2005.
- [4]Murata Y,Tamaki S,Yuda N,etc.A single administration of interleukin-4 antagonistic mutant DNA inhibits allergic airway inflammation in a mouse model of asthma.[J].2003,10(26).
- [5]Arnulf, Hartl,Richard, Weiss,Romana, Hochreiter,etc.Strategies for the development of safe and effective DNA vaccines for allergy treatment.[J].2003.
- [6]Peter S, Creticos,Lawrence M, Lichtenstein.Progress in the development of new methods of immunotherapy: potential application of immunostimulatory DNA-conjugated to allergens for treatment of allergic respiratory conditions.[J].2003,(94).