Abstract： A 27-year-old male presented with painful masses in the left inguinal region for 2 months and intermittent fever for 3 weeks.The lesion began as a dark erythematous papule in the left inguinal region,then enlarged and developed into ulcer,with adjacent lymphadenectasis,tenderness and intermittent fever.Physical examination revealed palpable infiltrated masses (measuring 4 cm in diameter) with central ulceration (measuring 1 cm in diameter),small amounts of serous hemorrhagic exudates and obvious haphalgesia in the left inguinal region.There were several broad bean-sized,enlarged and indurated lymph nodes with little mobility around the masses,which adhered and gave a trab-like appearance.Histopathology of the cutaneous masses revealed a dense patch-like atypical lymphoid cell infiltrate in deep dermis and subcutaneous fat tissue,and lymph node puncture showed clumps of atypical lymphoid cells.The infiltrating cells stained positive for CD30,CD43,CD45 and cytoplasmic ALK.The case was diagnosed as primary cutaneous ALKYD30+ anaplastic large cell lymphoma.After 3 courses of CEOP (cyclophosphamide,epirubicin,vincristine and prednisone acetate) chemotherapy,the masses subsided and the ulcer healed.