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Advances in the treatment of skin diseases with δ-aminolevulinic acid-based photodynamic therapy
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- Author:
- No author available
- Journal Title:
- INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1673-4173.2008.03.005
- Key Word:
- 氨基酮戊酸;光化学疗法;皮肤疾病;Aminolevulinic acid;Photochemotherapy;Skin diseases
Abstract： δ-aminolevulinic acid(ALA)-based photodynamic therapy(PDT)is a noninvasive topical treatment choice that can selectively kill target cells.One important mechanism for its therapeutic effect is to intluence some biological characteristics of target cells.Besides nonpigment cell malignant tumors of skin,ALA-PDT could be used in the treatment of premalignant lesions,viral warts,acne,connective tissue diseases,actinic skin diseases,and SO on.Appropriate higher temperature,cosolvents,metal chelating agents.iontoplaoretic delivery and liposome vector may enhance the therapeutic efrect of ALA-PDT.
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