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Prevalence and viral load of human papillomavirus in squamous cell carcinomas of the head and neck in different nationalities in Xingjiang area
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Oncology
- Issue:
- 11
- DOI:
- 10.3760/cma.j.issn.0253-3766.2014.11.010
- Key Word:
- 头颈部肿瘤;人乳头瘤病毒16;人乳头瘤病毒18;病毒载量;Head and neck neoplasms;Human papillomavirus 16;Human papillomavirus 18;Viral load
Abstract： 人乳头瘤病毒(human papillomavirus,HPV)感染已被证明是宫颈癌的一个重要病因[1].近年来,越来越多的研究表明,HPV高危型(16/18亚型)感染与头颈部鳞状细胞癌密切相关[2-4].因种族、文化、社会经济及地域差异,头颈部肿瘤的发病率存在很大差异.白种人患者感染HPV的概率是黑种人的10倍[5].由于HPV的感染存在着较明显的种族差异,我们利用逆转录聚合酶链反应(reverse transcriptasepolymerase chain reaction,RT-PCR)技术检测新疆维吾尔族、哈萨克族、汉族头颈部鳞状细胞癌中HPV感染情况,探讨新疆不同民族间头颈部鳞状细胞癌中HPV感染差异.
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