You Position: Home > Paper

A comparison of current guidelines for the management of intrahepatic cholangiocarcinoma worldwide

( views:166, downloads:26 )
Author:
No author available
Journal Title:
Chinese Journal of Surgery
Issue:
4
DOI:
10.3760/cma.j.cn112139-20221125-00495
Key Word:
胆管肿瘤;诊断;治疗;肝内胆管癌;临床指南;Bile duct neoplasms;Diagnosis;Treatment;Intrahepatic cholangiocarcinoma;Clinical guidelines

Abstract: Intrahepatic cholangiocarcinoma (ICC) is the second most common malignancy in the human liver and its incidence rate has been steadily increasing throughout the world over the past decades. Surgical resection (R0 resection) is the preferred potentially curative treatment for patients with ICC. However, due to its concealing clinical characteristics and high invasiveness, most patients have lost the opportunity for surgical resection at the time of diagnosis. In recent years, with the rapid development of targeted therapy and immunotherapy, represented by immunocheckpoint inhibitors, clinicians are expected to provide more effective treatment options for patients with mid-stage or advanced ICC. At present, there are still controversial opinions on different guidelines on preoperative biliary drainage, the extent of hepatectomy, the definition of R0 resection, the width of the resection margin, lymph node dissection, postoperative recurrence, adjuvant therapy, etc. In this review, 12 guidelines or expert consensus published worldwide from 2012 to 2022 (including 4 Chinese guidelines, 4 European guidelines, 2 American guidelines, and 2 Japanese guidelines) were retrieved. Focusing on sorting and comparing current views on clinical management of ICC in different guidelines, this review aims to provide reference information for clinical management and decision making of ICC.

  • This article has no references!
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn