Abstract： Photodynamic therapy(PDT) is an effective,minimally invasive method for tumor treatment. It can be applied to the treatment of cholangiocarcinoma in combination with the implementation of biliary stent/external biliary drainage or with systemic treatments, including chemotherapy. In addition, it is a primary application in the treatment of unresectable cholangiocarcinoma as well as an adjuvant treatment of residual postoperatively or locally recurrent tumors. It can control local tumor progression effectively,relieve biliary obstruction,improve quality of life, and prolong survival,with the advantages of being minimally invasive,precise and repeatable. To date, evidence-based clinical medicine for the application of PDT to treat cholangiocarcinoma has been limited,and there has been a lack of clinical specifications and consensus regarding the technique. Based on this,Group of Operative Surgery,Branch of Surgery,Chinese Medical Association, Group of Biliary Surgery, Branch of Surgery,Chinese Medical Association and Chinese Committee of Biliary Surgeons organized experts to discuss indications, contraindications, technical protocol, evaluation of efficacy, and management of complications when using PDT to treat cholangiocarcinoma. The consensus aims to provide a reference for promoting the clinical application of PDT in the treatment of cholangiocarcinoma.