You Position: Home > Paper
肝样腺癌的临床及病理学特点分析
( views:1188, downloads:1255 )
- Author:
- No author available
- Journal Title:
- Chinese Journal of Surgery
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.0529-5815.2019.02.013
- Key Word:
- No keyword available
Abstract： 肝样腺癌是一种非常罕见的特殊类型的腺癌,其原发于肝外,而形态学及免疫组织化学特征却与肝细胞癌相似.最初Ishikura等[1]因观察到一些胃腺癌患者高表达甲胎蛋白而提出肝样腺癌的概念.肝样腺癌可原发于不同的器官,其中胃是相对多的起源部位[2-3].胃肝样腺癌多见于老年患者,侵袭性强,生存率低,常常早期转移至肝脏和淋巴结,预后远劣于普通胃腺癌[4].早期发现并进行完整手术切除,是目前被认为能够治愈肝样腺癌的重要途径;鉴别肝细胞癌及肝样腺癌肝转移灶,寻找肝样腺癌原发部位至关重要.由于肝样腺癌发病率低,国内报道少,且患者的临床及影像学特征的特异性不高,易误诊或漏诊.我们报告13例肝样腺癌患者的临床病理特点、免疫表型及相关治疗,以期提高对该肿瘤的认识及诊断水平.
- [1]Bombski G,Gasiorowska A,Orszulak Michalak D,etc.Elevated plasma gastrin, CEA, and CA 19-9 levels decrease after colorectal cancer resection.[J].2003,18(2).
- [2]H, Ishikura,Y, Fukasawa,K, Ogasawara,etc.An AFP-producing gastric carcinoma with features of hepatic differentiation. A case report.[J].1985,56(4).
- [3]Fakhraddin Naghibalhossaini,Padideh Ebadi.Evidence for CEA release from human colon cancer cells by an endogenous GPI-PLD enzyme[J].2006,234(2).
- [4]Chu P,Wu E,Weiss LM.Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases.[J].2000,13(9).
- [5]P. Bazeries,M. Barral,M. Labrife,etc.Hepatic metastases from gastric hepatoid adenocarcinoma: An unusual cause of capsular retraction of the liver[J].2016,(9).
- [6]Jiann-Sheng Su,Yu-Tso Chen,Ren-Ching Wang,etc.Clinicopathological characteristics in the differential diagnosis of hepatoid adenocarcinoma:A literature review[J].2013,(3).
- [7]Simmet, Victor,Noblecourt, Margot,Lizee, Thibaut,etc.Chemotherapy of metastatic hepatoid adenocarcinoma: Literature review and two case reports with cisplatin etoposide[J].2018,15(1 Pt.A).
- [8]Van De Rijn M,Fan Z,Rouse RV,etc.Hep par 1 antibody stain for the differential diagnosis of hepatocellular carcinoma: 676 tumors tested using tissue microarrays and conventional tissue sections.[J].2003,16(2).
- [9]Xiangyu, Zeng,Peng, Zhang,Hua, Xiao,etc.Clinicopathological features and prognosis of intestinal hepatoid adenocarcinoma: evaluation of a pooled case series.[J].2018,9(2).
- [10]Chang, Min-Yung,Kim, Hye Jin,Park, Seung Hyun,etc.CT features of hepatic metastases from hepatoid adenocarcinoma[J].2017,42(10).