Abstract: Objective To study the surgical management of solid-pseudopapillary tumor of the pancreas (SPTP) and its characteristics of outcome.Methods Fifty-eight patients with SPTP of the pancreas admitted from January 2001 to December 2010 were retrospectively analyzed.There were 7 male and 51 female patients,with an average age of 30 years (rangeing 9 to 70 years).Most patients were symptomatic before admission; the most common symptom was abdominal pain.Of the 58 patients,21 patients underwent pancreaticoduodenectomy,30 patients underwent distal pancreatectomy,6 patients underwent central pancreatectomy,1 patient underwent simple tumor enucleation,and 1 patients underwent duodenum-preserving pancreatic head resection.Results The average length of stay in hospital was 23.8 days (ranging 12 to 64 days).Thirteen patients (22.4%) developed postoperative complications,including grade A postoperative pancreatic fistula of 8 cases,gastrointestinal tract bleeding of 1 case,pleural effusion of 2 cases,wound infection and fat liquefaction of 2 cases.Two patients underwent reoperation due to gastrointestinal tract bleeding or wound infection.There was no hospital death.Forty-four patients were followed-up for 7 to 136 months with an average of 41 months.All the 44 patients were alive,while 8 patients developed dyspepsia and 4 patients developed diabetes mellitus.There were no tumor recurrences or metastasis.Conclusions SPTP is found primarily in young women.Excellent prognosis would be achieved with surgical resection.