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~(125)I粒子抑制乳腺癌细胞TrKA表达的实验研究
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF SURGERY
- Issue:
- 19
- DOI:
- 10.3760/cma.j.issn.0529-5815.2009.19.018
- Key Word:
- No keyword available
Abstract： @@ 近年来随着诊断水平的不断提高,早期乳腺癌的诊断率越来越高,保乳手术也逐渐增多,乳腺癌局部切除结合~(125)I粒子组织间植入放疗是保乳手术的重要方法之一.但目前~(125)I粒子影响乳腺癌发生和转归的分子生物学机制尚不十分清楚,本实验通过构建裸小鼠乳腺癌细胞模型,植入~(125)I粒子,测量肿瘤组织内酪氨酸激酶原癌基因A(TrKA)的变化,以揭示~(125)I粒子治疗乳腺癌的生物学机制.
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