You Position: Home > Paper
Ultrasound-guided core needle biopsy in the diagnosis of breast lesions
( views:308, downloads:72 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF SURGERY
- Issue:
- 17
- DOI:
- 10.3760/j.issn:0529-5815.2007.17.011
- Key Word:
- 乳腺肿瘤;活组织检查,针吸;病理学,外科;超声,乳腺
Abstract： 目的 评价超声影像引导的乳腺病变经皮空芯针穿刺(CNB)组织病理检查方法的准确性及其影响因素.方法 回顾性分析2000年1月至2006年5月收治的2152例乳腺病变患者经皮CNB组织病理检查结果及临床资料.比较穿刺与切除组织病理诊断之间的一致性,并对未进行切除活检的患者进行随访.结果 在最终诊断为乳腺癌的1461例患者中,CNB病理结果显示,乳腺癌1339例,假阴性率为3.5%(51/1461),低估率为4.9%(71/1461).50.0%(17/34)的导管上皮非典型增生和46.3%(25/54)的乳头状病变在重新活检中诊断为癌.B超引导CNB的假阴性率(2.1%,22/1068)显著低于徒手引导CNB(7.4%,29/393)(P＜0.05).两名专责医师CNB的假阴性率(1.2%,8/681)显著低于非专责医师(5.5%,43/780)(P＜0.05).738例经CNB诊断良性病变中,417例进行手术切除活检,50例诊断为乳腺癌,205例良性病变随访2～29个月(中位随访时间10.2个月),发现1例恶性病变.结论 超声影像引导的乳腺病灶经皮病灶穿刺组织病理检查是准确可靠的诊断方法.对于穿刺病理结果为高危病变者应予切除活检.
- [1]欧阳涛,李金锋,王天峰,等.原发性乳腺癌经皮病灶穿刺组织病理学检查临床应用研究[J].2005,(23).
- [2]F, Burbank.Stereotactic breast biopsy: comparison of 14- and 11-gauge Mammotome probe performance and complication rates.[J].1997,63.
- [3]Nees AV,Helvie MA,Foster MC,etc.Lobular carcinoma in situ or atypical lobular hyperplasia at core-needle biopsy: is excisional biopsy necessary?[J].2004,231(3).
- [4]J.E. DAHLSTROM,S. SUTTON,S. JAIN.Histological precision of stereotactic core biopsy in diagnosis of malignant and premalignant breast lesions[J].1996,28(6).
- [5]Jackman RJ,Nowels KW,Rodriguez Soto-J,etc.Stereotactic, automated, large-core needle biopsy of nonpalpable breast lesions: false-negative and histologic underestimation rates after long-term follow-up.[J].1999,210(3).
- [6]Burbank F.Stereotactic breast biopsy of atypical ductal hyperplasia and ductal carcinoma in situ lesions: improved accuracy with directional, vacuum-assisted biopsy.[J].1997,202(3).