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Bcl-2融合蛋白对颅脑损伤细胞凋亡的影响
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NEUROSURGERY
- Issue:
- 2
- DOI:
- 10.3760/j.issn:1001-2346.2006.02.007
- Key Word:
- No keyword available
Abstract： @@ 颅脑损伤引起局部神经细胞受损死亡,包括坏死和凋亡两种形式.研究表明,在创伤性脑损伤后存在细胞凋亡相关基因的表达谱改变,其中Bcl-2的表达起着神经保护、减少受损细胞凋亡的作用[1].Bcl-2是在哺乳动物中最早发现的与凋亡有关的基因,属于Bcl-2基因家族,编码一个25-26KD的膜蛋白.
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