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Relationship between lipid peroxidation in blood and neurobehavioral function changes in coke oven workers
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- Author:
- No author available
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1001-9391.2007.01.004
- Key Word:
- 脂质过氧化作用;神经行为学表现;烃类,环
Abstract： 目的 探讨焦炉工体内脂质过氧化水平及其与神经行为的变化.方法将134名焦炉工分为炉底组35名、炉侧组49名、炉顶组50名,以36名原材料处工人为对照组进行神经行为功能测试,并检测血中总超氧化物歧化酶(T-SOD)活力,谷胱甘肽(GSH)、丙二醛(MDA)含量.结果 焦炉工血中T-SOD活力和GSH含量均明显低于对照组,差异有统计学意义(P＜0.01),疲惫-惰性、紧张-焦虑、忧郁-沮丧、有力-好动、数字跨度等指标明显低于对照组,差异有统计学意义(P＜0.05);而MDA含量明显高于对照组,差异有统计学意义(P＜0.01);相关分析表明,神经行为改变与脂质过氧化指标间有相关关系,但相关系数均小于0.25,相关关系较弱.结论 焦炉工体内脂质过氧化水平升高,并与其神经行为改变共存.
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