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Application of MALDI-TOF MS in detection of bacterial resistance mechanisms

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Author:
No author available
Journal Title:
Chinese Journal of Clinical Infectious Diseases
Issue:
6
DOI:
10.3760/cma.j.issn.1674-2397.2017.06.014
Key Word:
细菌;耐药机制;基质辅助激光解吸电离飞行时间质谱;Bacteria;Resistance mechanisms;MALDI-TOF MS

Abstract: Bacterial resistance has become a serious problem that the whole world is facing.Routine bacterial drug resistance testing methods such as K-B test and dilution method are time-consuming and incapable to identify the specific drug resistance mechanism , which can not meet the needs of clinicians. MALDI-TOF MS overcomes the shortcomings of traditional methods and has broad application prospects in detection of bacterial resistance and drug resistance mechanism.This article reviews the recent progress on the application of MALDI-TOF MS in detection of bacterial drug resistance mechanisms.

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