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Research progress on microRNAs involvement in liver diseases

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Author:: No author available

Journal Title:: Chinese Journal of Clinical Infectious Diseases

Issue:: 2

DOI:: 10.3760/cma.j.issn.1674-2397.2015.02.023

Key Word:: 微RNAs;肝疾病;诊断;治疗;MicroRNAs;Liver diseases;Diagnosis;Therapy

Abstract： MicroRNAs (miRNAs) are small non-coding RNAs that regulate both mRNA and protein expression of target genes and play important roles in proliferation,differentiation,development and metabolism of cells.This paper reviews the research progress on miRNAs involvement in liver diseases,including viral hepatitis,fatty liver,drug induced liver disease,primary biliary cirrhosis and primary hepatocellular carcinoma.

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