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Antibiotic resistance and gene typing of Streptococcus pneumoniae of susceptible and non-susceptible in penicillin

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF CLINICAL INFECTIOUS DISEASES
Issue:
3
DOI:
10.3760/cma.j.issn.1674-2397.2011.03.013
Key Word:
链球菌,肺炎;抗药性;基因;儿童;Streptococcus pneumoniae;Drug resistance;Gene;Children

Abstract´╝Ü 肺炎链球菌是社区获得性呼吸道感染的重要致病菌,不仅可引起普通感染如中耳炎、鼻窦炎等,还可引起肺炎、败血症和化脓性脑膜炎等侵袭性疾病,每年导致300万儿童死亡.青霉素一直是治疗肺炎链球菌感染的首选抗生素,自20世纪80年代以来,耐青霉素肺炎链球菌(penicillin resistant Streptococcus pneumoniae,PRSP)开始在世界范围内流行.PRSP不仅对青霉素耐药,对其他β-内酰胺类、大环内酯类等也耐药,且其耐药率存在地域差异,给临床治疗和患者预后带来不良影响[1].

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