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Linezolid for treatment of infective endocarditis caused by methicillin-resistant Staphylococcus aureus: report of one successful case
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF CLINICAL INFECTIOUS DISEASES
- Issue:
- 6
- DOI:
- 10.3760/cma.j.issn.1674-2397.2010.06.017
- Key Word:
- 葡萄球菌,金黄色;甲氧西林抗药性;利奈唑胺;感染性心内膜炎;Staphylococcus aureus;Methicillin resistance;Linezolid oxazolidinone;Infective endocarditis
Abstract： @@ 患者女,21岁,以"发热4 d"为主诉入院.患者4 d前受凉后出现高热,体温最高达41 ℃,伴寒颤、剧烈头痛.入院时神志清,表情淡漠,全身皮肤、黏膜多处可见出血点,扁桃体Ⅰ度肿大,二尖瓣听诊区可闻及2/6级吹风样杂音.血常规查白细胞(WBC)11.64×109/L,中性粒细胞为0.896,颅内压为230 mm H2O(1 mm H2O=0.0098 kPa),脑脊髓液及头颅磁共振成像(MRI)均未见异常.连续3次血培养均为耐甲氧西林金黄色葡萄球菌(MRSA),对万古霉素、替考拉宁和利奈唑胺敏感.
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