You Position: Home > Paper
慢性阻塞性肺疾病管理中吸入装置的选择与应用
( views:566, downloads:1567 )
- Author:
- No author available
- Journal Title:
- Chinese Journal of Tuberculosis and Respiratory Diseases
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1001.0939.2020.01.018
- Key Word:
- No keyword available
Abstract： 慢性阻塞性肺疾病(慢阻肺)已成为我国第三大致死性疾病,疾病负担重.吸入疗法作为慢阻肺治疗的首选给药方式,起效快速、使用方便;但临床仍存在医患对吸入装置特性认识不足、吸入装置使用不当、吸入药物选择不同、吸入方法掌握不妥等情况,导致患者症状控制不佳、急性加重增多的情况时有发生.本文将重点介绍吸入药物的类型和作用机制、吸入装置的种类和特点、影响吸入药物疗效的因素等,以利于医护人员指导患者正确选择和使用吸入装置,从而实现慢阻肺的全程规范化管理.
- [1]韩飞,赵志冬,王跃生,等.肺部吸入制剂评价方法的研究进展[J].2012,(11).
- [2]舒宏,崔一民,侯曙光.肺部吸入给药制剂及临床应用[J].2014,(2).
- [3]李材忠.慢性阻塞性肺疾病稳定期患者院外使用吸入制剂的依从性分析[J].2018,(8).
- [4]中国医学装备协会呼吸病学专委会吸入治疗与呼吸康复学组,中国慢性阻塞性肺疾病联盟.稳定期慢性气道疾病吸入装置规范应用中国专家共识[J].2019,(4).
- [5]Sinthia, Bosnic-Anticevich,Henry, Chrystyn,Richard W, Costello,etc.The use of multiple respiratory inhalers requiring different inhalation techniques has an adverse effect on COPD outcomes.[J].2017,12(Spec ).
- [6]Ghosh, Sohini,Ohar, Jill A.,Drummond, M. Bradley.Peak Inspiratory Flow Rate in Chronic Obstructive Pulmonary Disease: Implications for Dry Powder Inhalers[J].2017,30(6).
- [7]R K, Wolff,R W, Niven.Generation of aerosolized drugs.[J].1994,7(1).
- [8]Dieter, Hochrainer,Hubert, H?lz,Christoph, Kreher,etc.Comparison of the aerosol velocity and spray duration of Respimat Soft Mist inhaler and pressurized metered dose inhalers.[J].2005,18(3).
- [9]主编朱元珏, 陈文彬.呼吸病学[M].2003.
- [10]Pablo, Altman,Luis, Wehbe,Juergen, Dederichs,etc.Comparison of peak inspiratory flow rate via the Breezhaler?, Ellipta? and HandiHaler? dry powder inhalers in patients with moderate to very severe COPD: a randomized cross-over trial.[J].2018,18(1).
- [11]Richard N, Dalby,Joachim, Eicher,Bernd, Zierenberg.Development of Respimat(?) Soft Mist? Inhaler and its clinical utility in respiratory disorders.[J].2011,4.
- [12]Job, van der Palen,Mike, Thomas,Henry, Chrystyn,etc.A randomised open-label cross-over study of inhaler errors, preference and time to achieve correct inhaler use in patients with COPD or asthma: comparison of ELLIPTA with other inhaler devices.[J].2016,(Spec ).
- [13]Ana Fernández Tena,Pere Casan Clarà.Depósito pulmonar de partículas inhalada[J].2012,48(7).
- [14]Wang, Chen,Xu, Jianying,Yang, Lan,etc.Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study[J].2018,391(10131).
- [15]Donald E. Morisky,Alfonso Ang,Marie Krousel-Wood,etc.Predictive Validity of a Medication Adherence Measure in an Outpatient Setting[J].2008,10(5).
- [16]Mathieu Molimard Peter D'Andrea.Once-daily glycopyrronium via the Breezhaler? device for the treatment of COPD: pharmacological and clinical profile[J].2013,6(5).
- [17]M, Molimard,C, Raherison,S, Lignot,etc.Assessment of handling of inhaler devices in real life: an observational study in 3811 patients in primary care.[J].2003,16(3).
- [18]C, Terzano,F, Oriolo.Lung characteristics in elderly males and females patients with COPD: differences and optimal use of dry powder inhalers (DPIs).[J].2017,21(11).
- [19]Walter, Vincken,Pn Richard, Dekhuijzen,Peter, Barnes.The ADMIT series - Issues in inhalation therapy. 4) How to choose inhaler devices for the treatment of COPD.[J].2010,19(1).
- [20]Martucci P,Scichilone N,Sestini P,etc.Inhaler mishandling remains common in real life and is associated with reduced disease control.[J].2011,105(6).
- [21]Grant, Andrew C.,Garrill, Karl,Hamilton, Melanie,etc.The ELLIPTA (R) Dry Powder Inhaler: Design, Functionality, In Vitro Dosing Performance and Critical Task Compliance by Patients and Caregivers[J].2015,28(6).
- [22]Meng, Xia,Ma, Yanjun,Chen, Renjie,etc.Size-Fractionated Particle Number Concentrations and Daily Mortality in a Chinese City[J].2013,121(10/12).
- [23]Molimard, Mathieu,Raherison, Chantal,Lignot, Severine,etc.Chronic obstructive pulmonary disease exacerbation and inhaler device handling: real-life assessment of 2935 patients[J].2017,49(2).
- [24]Chi-Yen, Liang,Yi-Jen, Chen,Shew-Meei, Sheu,etc.Misuse of inhalers among COPD patients in a community hospital in Taiwan.[J].1900,13.
- [25]Lipson, David A.,Barnhart, Frank,Brealey, Noushin,etc.Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD[J].2018,378(18).