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肌肉生长抑制蛋白对慢性阻塞性肺疾病合并肺动脉高压患者的预测意义
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Tuberculosis and Respiratory Diseases
- Issue:
- 7
- DOI:
- 10.3760/cma.j.issn.1001-0939.2017.07.012
- Key Word:
- No keyword available
Abstract： 慢性阻塞性肺疾病(慢阻肺)合并肺动脉高压的发病率和病死率很高[1].右心导管检查仍是诊断肺动脉高压的金标准,但在临床实际工作中往往难以实现[2],依靠经胸超声心动图对右心功能进行评估[3].近年来文献报道肌肉生长抑制蛋白(myostatin)在容量负荷所致的心力衰竭模型中表达增高[4-5],在慢性肺源性心脏病患者中也有类似报道[6].本研究通过观察慢阻肺合并肺动脉高压患者血液中肌肉生长抑制蛋白的水平,探讨其与慢阻肺合并肺动脉高压的关系.
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