You Position: Home > Paper
New concepts in chronic obstructive pulmonary disease and cor pulmonale
( views:551, downloads:1354 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1001-0939.2011.04.004
- Key Word:
- No keyword available
Abstract： @@ COPD属于常见病、多发病,并在人类致死病因中名列前茅.COPD发病率在中国40岁以上人群中高达8.2%[1],也就是说在中国13亿人口中可能有上千万例COPD患者.显然,这一巨大的患者群势必给人民健康与卫生资源造成沉重负担.COPD最常见和最严重的并发症是肺动脉高压与肺源性心脏病.传统上,COPD→肺动脉高压→肺源性心脏病被视为同一疾病过程逐渐加重的必然定式,临床表现为从最初的呼吸系统症状最终发展为右心功能衰竭.近年来,随着基础与临床研究的进展,这一定式似乎开始受到怀疑[25].本文综述有关方面的最新进展,重点介绍对COPD概念的新以识.
- [1]翟振国,谢万木,杨媛华,等.慢性阻塞性肺疾病相关性肺动脉高压研究中需要关注的几个问题[J].2008,(5).
- [2]Palange P.Renal and hormonal abnormalities in chronic obstructive pulmonary disease (COPD).[J].1998,53(11).
- [3]A J, Crottogini,P, Willshaw.Calculating the end-systolic pressure-volume relation.[J].1991,83.
- [4]Minai OA,Chaouat A,Adnot S.Pulmonary hypertension in COPD: epidemiology, significance, and management: pulmonary vascular disease: the global perspective.[J].2010,137(6 Suppl.).
- [5]E J, CAMPBELL,D S, SHORT.The cause of oedema in "corpulmonale".[J].1960,1.
- [6]Blanco,I.,Gimeno,E.,Munoz,P.A.,etc.Hemodynamic and gas exchange effects of sildenafil in patients with chronic obstructive pulmonary disease and pulmonary hypertension[J].2010,181(3).
- [7]R L, Qiao,J, Bhattacharya.Segmental barrier properties of the pulmonary microvascular bed.[J].1991,71.
- [8]Criner G,Iqbal M,Keller C,etc.Hemodynamic characterization of patients with severe emphysema.[J].2002,166(3).
- [9]Ari Chaouat,Laurent Savale,Christos Chouaid,etc.Role for lnterleukin-6 in COPD-Related Pulmonary Hypertension[J].2009,136(3).
- [10]Zhong N,Wang C,Yao W,etc.Prevalence of chronic obstructive pulmonary disease in China: a large, population-based survey.[J].2007,176(8).
- [11]Barbera JA,Blanco I.Pulmonary hypertension in patients with chronic obstructive pulmonary disease: advances in pathophysiology and management.[J].2009,69(9).
- [12]Macnee W.Right heart function in COPD.[J].2010,31(3).
- [13]Chaouat A,Weitzenblum E,Canuet M.Pulmonary hypertension in chronic obstructive pulmonary disease and interstitial lung diseases.[J].2009,30(4).
- [14]Nussbaumer Ochsner Y,Rabe KF.Systemic manifestations of COPD.[J].2011,139(1).