You Position: Home > Paper
辛伐他汀和他达拉非对野百合碱致肺动脉高压大鼠肺血管重塑的影响
( views:210, downloads:104 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 12
- DOI:
- 10.3760/cma.j.issn.1001-0939.2009.12.027
- Key Word:
- No keyword available
Abstract： @@ 肺动脉高压是多种病因引起的一种临床病理牛理综合征,表现为肺血管阻力和肺动脉压力进行性增高,最终可因右心衰竭而导致患者死亡.肺血管重塑引起的肺小动脉的狭窄和闭塞是肺动脉高压发生和发展的病理基础.
- [1]Seybert A,Benedict N,Mathier MA.Evidence-based pharmacologic management of pulmonary arterial hypertension.[J].2007,29(10).
- [2]Tan HL,Michel MC,Hardziyenka M,etc.How valid are animal models to evaluate treatments for pulmonary hypertension?[J].2006,373(6).
- [3]Kwak B,Mulhaupt F,Myit S,etc.Statins as a newly recognized type of immunomodulator.[J].2000,6(12).
- [4]Benza RL,Park MH,Keogh A,etc.Management of pulmonary arterial hypertension with a focus on combination therapies.[J].2007,26(5).
- [5]Barst RJ,Fleming T,Parpia T,etc.Sildenafil citrate therapy for pulmonary arterial hypertension.[J].2005,353(20).
- [6]Hermanowski-Vosatka A,Hernandez M,Mundt S,etc.Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering.[J].2001,21(1).
- [7]Murata T,Sato K,Hori M,etc.Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension.[J].2002,277(46).
- [8]Nishimura T,Berry GJ,Pearl RG,etc.Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats.[J].2002,166(10).
- [9]Sharma R.Novel phosphodiesterase-5 inhibitors: Current indications and future directions.[J].2007,61(12).