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罗格列酮对支气管哮喘急性发作期患者T淋巴细胞IL-4/STAT6信号通路的影响及机制
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 11
- DOI:
- 10.3321/j.issn:1001-0939.2008.11.011
- Key Word:
- No keyword available
Abstract： @@ Th1/Th2细胞比例失调和Th2细胞优势分化是支气管哮喘(简称哮喘)发病的免疫学基础.白细胞介素(IL)-4是诱导Th2细胞分化的关键细胞因子;信号传导和转录激活子6(STFAT6)是Th2细胞的特异性转录因子;IL-4的许多功能的发挥都要通过与IL-4R结合,继而由STAT6介导炎症基因转录.
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