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Advances in molecular imaging by targeting macrophages of atherosclerosis vulnerable plaques

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Author:: No author available

Journal Title:: Chinese Journal of Nuclear Medicine and Molecular Imaging

Issue:: 8

DOI:: 10.3760/cma.j.cn321828-20210103-00002

Key Word:: 斑块，动脉粥样硬化;分子显像;巨噬细胞;发展趋势;Plaque, atherosclerotic;Molecular imaging;Macrophages;Trends

Abstract： Vulnerable plaque rupture is the leading cause of acute cardiovascular diseases. Macrophages are main inflammatory cells closely related to the rupture of vulnerable plaques. Early diagnosis of vulnerable plaque can reduce the mortality of acute cardiovascular diseases. With the development of molecular imaging, the possibility for early identification of vulnerable plaques may come true. This review summarizes the changes of molecular markers of macrophages in vulnerable plaques and the molecular probes that can target macrophages.

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